| Alan Alda as | Arnold Vinick | Former Republican Candidate for President |
| Kristin Chenoweth as | Annabeth Schott | Santos / McGarry Campaign Staffer |
| Dulé Hill as | Charlie (Charles) Young | Deputy Special Assistant to the Chief of Staff |
| Allison Janney as | C.J. (Claudia Jean) Cregg | Chief of Staff |
| Joshua Malina as | Will (William) Bailey | Vice President's Chief of Staff |
| Mary McCormack as | Kate (Katherine) Harper | Deputy National Security Advisor |
| Janel Moloney as | Donna (Donnatella) Moss | Santos Transition Staffer |
| Bradley Whitford as | Josh (Joshua) Lyman | Santos' Chief of Staff |
| with Jimmy Smits as |
Matthew Vincente Santos | President-Elect |
| and Martin Sheen as |
Jed (Josiah Edward) Bartlet | President of the United States |
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