| Alan Alda as | Arnold Vinick | Former Republican Candidate for President |
| Allison Janney as | C.J. (Claudia Jean) Cregg | Chief of Staff |
| with Jimmy Smits as |
Matthew Vincente Santos | President-Elect |
| Special Guest Stars | ||
| Mary-Louise Parker as | Amy (Amelia) Gardner | Santos' Transition |
| Teri Polo as | Helen Santos | Matt Santos' Wife |
| Patricia Richardson as | Sheila Brooks | Former Vinick Campaign Manager |
| and Janeane Garofalo as |
Louise "Lou" Thornton | Santos Director of Communications |
| Guest Starring | ||
| Stephen Root as | Bob Mayer | Vinick Speechwriter |
| Michael O'Neill as | Ron Butterfield | Head of POTUS' Secret Service detail |
| John Aylward as | Barry Goodwin | Former DNC Chairman |
| NiCole Robinson as | Margaret Hooper | Assistant to Chief of Staff |
| David Clennon as | Jim | Vinick's Lawyer |
| Karis Campbell as | Ronna (Beckman) | Santos' Aide |
| Marlene Forte as | Linda | Secret Service Agent |
| Bonita Friedericy as | Gail Addison | Office of Administration |
| Adrian Sparks as | Dr. Wexler | Vinick's Doctor |
| Co-Starring | ||
| Ashlyn Sanchez as | Miranda Santos | Santos' Daugther |
| Joshua Cabrera as | Peter Santos | Santos' Son |
| Annie Morgan as | Annie | Vinick Staffer |
| Paul Keeley as | Agent Taylor | Ellis (first name) |
| Ivan Allen as | Anchor | Roger Salier |
| Van Epperson as | Curtis Schaefer | Chief Usher |
| Alexandra Ryan as | Receptionist | Santos Transition |
| Parvesh Cheena as | Barista | |
| Maria Broom as | Cathy Holland | Pulic School |
"We'll have episodes at the end where we'll follow (chief of staff) C.J. Cregg (Allison Janney) and see what is happening in her life. There is an episode about what happens to (disgraced speechwriter) Toby (Richard Schiff). We have a full episode with what is happening with Vinick and Santos, what is happening in the rest of the their lives. We will have an episode about (Santos' campaign manager) Josh Lyman (Bradley Whitford) and an episode about Bartlet (Martin Sheen). "It was going to be an episode about Bartlet and Leo. Now it will be an episode about Bartlet."
"'West Wing' deals with its final days"
by Alan Pergament
January 25, 2006
Buffalo News
O'Donnell, who was charged with writing Vinick, called it "my greatest pleasure on 'The West Wing,' especially since I once said that it would never be a Republican political show."He said his mind was changed after attending the 2004 GOP convention in New York and seeing the party's future in people like former New Jersey governor Christie Whitman, mayors Rudy Giuliani and Michael Bloomberg, and Gov. Arnold Schwarzenegger: politicians who are liberal on some issues, conservative on others.
"Sun sets on 'West Wing'"
by Aaron Barnhart
May 14, 2006
Kansas City Star