| Stockard Channing as | Abbey (Abigail Ann) Bartlet M.D. | First Lady |
| Allison Janney as | C.J. (Claudia Jean) Cregg | Chief of Staff |
| Joshua Malina as | Will (William) Bailey | Communications Director |
| Mary McCormack as | Kate (Katherine) Harper | Deputy National Security Advisor |
| Janel Moloney as | Donna (Donnatella) Moss | Santos / McGarry Campaign Staffer |
| John Spencer as | Leo Thomas McGarry | Democratic Candidate for Vice President |
| Bradley Whitford as | Josh (Joshua) Lyman | Santos Campaign Manager |
| with Jimmy Smits as |
Matthew Vincente Santos | Democratic Candidate for President |
| and Martin Sheen as |
Jed (Josiah Edward) Bartlet | President of the United States |
| Special Guest Stars | ||
| Janeane Garofalo as | Louise "Lou" Thornton | Santos / McGarry Director of Communications |
| and Lily Tomlin as |
Debbie (Deborah) Fiderer | President's Secretary |
| Guest Starring | ||
| Nina Siemaszko as | Ellie (Eleanor Emily) Bartlet | Bartlets' middle daughter |
| Ben Weber as | Vic Faison | Ellie's Fiancée |
| Steve Ryan as | Miles Hutchinson | Secretary of Defense |
| John Aylward as | Barry Goodwin | Former DNC Chairman |
| Robert Foxworth as | Senator George Montgomery | |
| Matthew Del Negro as | Bram (Howard) | Santos / McGarry Campaign Staffer |
| Diana-Maria Riva as | Edie (Edith) Ortega | Deputy Campaign Manager for Strategic Planning |
| Richard Jenik as | Congressman Cooper | D-WI |
| Co-Starring | ||
| Melissa Fitzgerald as | Carol | Fitzpatrick (last name) Assistant to the Press Secretary |
| Jan Devereaux as | Shirley | Social Secretary |
| Ron Ostrow as | John | Reporter |
| Joyce Guy as | Charlayne | Reporter |
| Dougald Park as | Stan Mitchell | Chicago DNC Field Op |
| Yvans Jourdain as | Bermudian Ambassador | |
| Linden Goh as | Translator |
Janney and her fiance, actor Richard Jenik, 37, a native of Delanco, Burlington County, are aiming to wed this spring. It's the first marriage for both.
"Allison Janney's at center of a shakeup on 'West Wing'"
by Gail Shister
November 2, 2004
Philadelphia Inquirer
The Tribune urges the election of Democrat Matthew V. Santos as president of the United States.OK, so maybe there really isn't an imminent election and maybe there really isn't a Matthew V. Santos. But we have endorsed him, anyway. Sort of. An explanation is in order.
...
Santos has been the underdog. But in last Sunday's episode, new polls showed he was pulling within striking distance of Vinick. The Santos camp was especially heartened by results from Illinois, where the candidate had cut a 9-point deficit down to 4. Santos credited the surge to his Chicago Tribune endorsement.
"It's gotta be the Trib," declared Santos' running mate, Leo McGarry.
...
But thanks for the credit, "West Wing" script writers. We didn't actually do anything. But if we had, here's a rare peek into the super-secret endorsement deliberations at the Tribune editorial board:
The Vinick character may be a moderate Republican. But he reminds us an awful lot of Alan Alda, the ex-"M*A*S*H" star linked to just about every touchy-feely cause imaginable.
Meanwhile, Santos looks a lot like actor Jimmy Smits, who for years played police detective Bobby Simone on "NYPD Blue." Simone was strength and compassion incarnate.
So at gut check time, Democrat Santos became our easy pick for the endorsement.
"Matthew V. Santos for president"
December 16, 2005
Chicago Tribune
Spencer appeared in seven of the 14 episodes that have been filmed, nine of which have been broadcast.
"How series deal with death"
by William Keck
December 18, 2005
USA Today