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| Alan Alda (uncredited) as | Arnold Vinick | Senator R-CA |
| Stockard Channing as | Abbey (Abigail Ann) Bartlet M.D. | First Lady |
| Dulé Hill as | Charlie (Charles) Young | Deputy Special Assistant to the Chief of Staff |
| Allison Janney as | C.J. (Claudia Jean) Cregg | Chief of Staff |
| Mary McCormack as | Kate (Katherine) Harper | Deputy National Security Advisor |
| Richard Schiff as | Toby (Tobias Zachary) Ziegler | Communications Director |
| John Spencer as | Leo Thomas McGarry | Former Chief of Staff |
| and Martin Sheen as |
Jed (Josiah Edward) Bartlet | President of the United States |
| Special Guest Stars | ||
| Kristin Chenoweth as | Annabeth Schott | Deputy Press Secretary |
| Christopher Lloyd as | Lawrence Lessig | Constitutional Law Professor |
| with Roger Rees as |
Lord John Marbury | British Ambassador to the United States |
| Guest Starring | ||
| Steve Ryan as | Miles Hutchinson | Secretary of Defense |
| Elya Baskin as | Mr. Zubatov | Sovetskaya Belorussiya Editor in Chief |
| Anthony Azizi as | Chet | Asefi Hossein Kamal Bin Hamid |
| NiCole Robinson as | Margaret | Hooper (last name) / Assistant to Chief of Staff |
| Renée Estevez as | Nancy | Aide |
| Co-Starring | ||
| Melissa Fitzgerald as | Carol | Fitzpatrick (last name) Assistant to the Press Secretary |
| Peter James Smith as | Ed | Congressional Liaison |
| William Duffy as | Larry | Congressional Liaison |
| Ben Murray as | Curtis Carruthers | Personal Aide to the President |
| Charles Noland as | Steve | Reporter |
| Ron Ostrow as | John | Reporter |
| Tom W. Chick as | Gordon | Reporter |
| Penny Griego as | Newscaster | |
| Derek Coleman as | Secret Service | |
| Pamela Salem as | P.M. Maureen Graty | British Prime Minister |
| Oleg Vidov as | Lipecki | Igor (first name) / Belarusian Judge |
| Edward Shkolnikov as | Helakal | Vlad (first name) / Belarusian Legislator |
| Claudia Lynx as | Miss World | Lyonpo Palden Wangchuk |
| Ken Weiler as | Officer |
The president's wife, Abb[e]y (Stockard Channing), will begin a storyline, shortly before Christmas, that will reintroduce the issue of the president's multiple sclerosis.
"New flight for 'West Wing'"
by Mike McDaniel
October 14, 2004
Houston Chronicle
"They're both ensemble shows [ER and The West Wing], they're both very fast-paced, and they're both these big animals -- every week, there's a lot going on," she says. "So they don't feel that different. ... I enjoy the kind of language- and intellect-based world of 'The West Wing,' where people are discussing ideas. - Laura Innes
"Innes Pulls Double Duty on 'West Wing,' 'ER'"
February 9, 2005
zap2it.com
Lawrence Lessig, a Stanford University professor who is a leading American intellectual property scholar known as "the Elvis of cyber law," has now achieved a measure of fame among fans of "The West Wing." In Wednesday night's episode, "The Wake Up Call," Christopher Lloyd ("Back to the Future") made a guest appearance as Prof. Lawrence Lessig, a Harvard University legal expert enlisted to explain particulars of the Constitution to members of a delegation from Belarus as they write a new, democratic constitution. The character is based on the screenwriter Josh Singer's real-life mentor, Professor Lessig, with whom he studied contract law at Harvard in 1997. "It was one of my first courses, and he was unbelievable," Mr. Singer said. "He was a rock star." In preparing for the episode, Mr. Singer also remembered that Professor Lessig had been asked, in his capacity as co-director of the Center for the Study of Constitutionalism in Eastern Europe, to help work on the Georgian constitution. "I called him up and asked him to tell me more about what had happened," Mr. Singer said. "On the set, we replicated what they had done." No word yet on the real-life professor's feeling about the episode, though Mr. Singer said that after reading the script and giving formal approval, his mentor "seemed to be pretty thrilled."
"A Professor's Fame"
Compiled By Lawrence Van Gelder
February 9, 2005
New York Times
On "The West Wing," Sheen plays a president who finds ways to do his job despite multiple sclerosis. A University of California consultant has advised Sheen on how to play the struggle with the disease."What she told me was to be subtle. I can have many ups and downs," he said.
Subtle and optimistic. "(MS) patients see the light at the end of the tunnel," Sheen said.
Sheen isn't an official spokesman for MS because, unlike his character, he doesn't have the disease.
"Sheen shuns political aspirations"
by Dave Mason
February 18, 2005
Scripps Howard News Service